Review



rbfox1 transgenic mice human rbfox1 cdna  (Addgene inc)


Bioz Verified Symbol Addgene inc is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    Addgene inc rbfox1 transgenic mice human rbfox1 cdna
    Rbfox1 Transgenic Mice Human Rbfox1 Cdna, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+rbfox1+cdna/pENTR-A2BP1+(Plasmid+%2316176)/pm41928095-78-2-10
    Average 93 stars, based on 6 article reviews
    rbfox1 transgenic mice human rbfox1 cdna - by Bioz Stars, 2026-09
    93/100 stars

    Images

    Related Articles

    Clone Assay:

    Article Title: Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology
    Article Snippet: .. Human RBFOX1 cDNA (from pENTR-A2BP1, Addgene, 16176) or human U2AF2 cDNA (from pCDNA3-U2AF65-DYK, GenScript, OHu17874) were independently cloned into a plasmid containing a bidirectional TetO sequence that also harbors the β-galactosidase (β-Gal) reporter with a NLS (pBI-G, Clontech, 631004). ..

    Plasmid Preparation:

    Article Title: Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology
    Article Snippet: .. Human RBFOX1 cDNA (from pENTR-A2BP1, Addgene, 16176) or human U2AF2 cDNA (from pCDNA3-U2AF65-DYK, GenScript, OHu17874) were independently cloned into a plasmid containing a bidirectional TetO sequence that also harbors the β-galactosidase (β-Gal) reporter with a NLS (pBI-G, Clontech, 631004). ..

    Sequencing:

    Article Title: Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology
    Article Snippet: .. Human RBFOX1 cDNA (from pENTR-A2BP1, Addgene, 16176) or human U2AF2 cDNA (from pCDNA3-U2AF65-DYK, GenScript, OHu17874) were independently cloned into a plasmid containing a bidirectional TetO sequence that also harbors the β-galactosidase (β-Gal) reporter with a NLS (pBI-G, Clontech, 631004). ..



    Similar Products

    rbfox1 transgenic mice human rbfox1 cdna  (Addgene inc)
    93
    Addgene inc rbfox1 transgenic mice human rbfox1 cdna
    Rbfox1 Transgenic Mice Human Rbfox1 Cdna, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+rbfox1+cdna/pENTR-A2BP1+(Plasmid+%2316176)/pm41928095-78-2-10
    Average 93 stars, based on 1 article reviews
    rbfox1 transgenic mice human rbfox1 cdna - by Bioz Stars, 2026-09
    93/100 stars
    		  Buy from Supplier
    human rbfox1 cdna  (Addgene inc)
    93
    Addgene inc human rbfox1 cdna
    ( A ) Normalized counts of the three RBFOX genes in striatal RNA from 3.5 month-old WT (n=3) and R6/1 mice (n=3) according to RNA-seq datasets in Elorza et al . 15 ( B ) Quantification of <t>Rbfox1</t> transcript levels by RT-qPCR in striatal RNA from 3.5 month-old WT (n=7) and R6/1 mice (n=7) (Student’s t-test; * P < 0.05). ( C ) Rbfox1 immunohistochemistry in striatum of 3.5 month-old WT and R6/1 mice. ( E ) Representative RBFOX1 immunohistochemistry staining in striatum of control and HD subjects.
    Human Rbfox1 Cdna, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+rbfox1+cdna/pENTR-A2BP1+(Plasmid+%2316176)/bio_rxiv__2024__11__06__622223-111-0-5
    Average 93 stars, based on 1 article reviews
    human rbfox1 cdna - by Bioz Stars, 2026-09
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    ( A ) Normalized counts of the three RBFOX genes in striatal RNA from 3.5 month-old WT (n=3) and R6/1 mice (n=3) according to RNA-seq datasets in Elorza et al . 15 ( B ) Quantification of Rbfox1 transcript levels by RT-qPCR in striatal RNA from 3.5 month-old WT (n=7) and R6/1 mice (n=7) (Student’s t-test; * P < 0.05). ( C ) Rbfox1 immunohistochemistry in striatum of 3.5 month-old WT and R6/1 mice. ( E ) Representative RBFOX1 immunohistochemistry staining in striatum of control and HD subjects.

    Journal: bioRxiv

    Article Title: Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology

    doi: 10.1101/2024.11.06.622223

    Figure Lengend Snippet: ( A ) Normalized counts of the three RBFOX genes in striatal RNA from 3.5 month-old WT (n=3) and R6/1 mice (n=3) according to RNA-seq datasets in Elorza et al . 15 ( B ) Quantification of Rbfox1 transcript levels by RT-qPCR in striatal RNA from 3.5 month-old WT (n=7) and R6/1 mice (n=7) (Student’s t-test; * P < 0.05). ( C ) Rbfox1 immunohistochemistry in striatum of 3.5 month-old WT and R6/1 mice. ( E ) Representative RBFOX1 immunohistochemistry staining in striatum of control and HD subjects.

    Article Snippet: Human RBFOX1 cDNA (from pENTR-A2BP1, Addgene, 16176) or human U2AF2 cDNA (from pCDNA3-U2AF65-DYK, GenScript, OHu17874) were independently cloned into a plasmid containing a bidirectional TetO sequence that also harbors the β-galactosidase (β-Gal) reporter with a NLS (pBI-G, Clontech, 631004).

    Techniques: RNA Sequencing, Quantitative RT-PCR, Immunohistochemistry, Staining, Control

    ( A ) Mice expressing tTA under control of the CamKII promoter (CamKII-tTA mice) were bred with mice carrying the β-Gal-BiTetO-RBFOX1 or β-Gal-BiTetO-U2AF2 construct to yield TgRBFOX1 (CamKII-tTA:β-Gal-BiTetO-RBFOX1) mice or TgU2AF2 (CamKII-tTA:β-Gal-BiTetO-U2AF2) . ( B ) Immunohistochemistry with anti-RBFOX1 or anti-U2AF2 antibody in sagittal sections from 1.5 month-old WT, TgRBFOX1 or TgU2AF2 mice.

    Journal: bioRxiv

    Article Title: Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology

    doi: 10.1101/2024.11.06.622223

    Figure Lengend Snippet: ( A ) Mice expressing tTA under control of the CamKII promoter (CamKII-tTA mice) were bred with mice carrying the β-Gal-BiTetO-RBFOX1 or β-Gal-BiTetO-U2AF2 construct to yield TgRBFOX1 (CamKII-tTA:β-Gal-BiTetO-RBFOX1) mice or TgU2AF2 (CamKII-tTA:β-Gal-BiTetO-U2AF2) . ( B ) Immunohistochemistry with anti-RBFOX1 or anti-U2AF2 antibody in sagittal sections from 1.5 month-old WT, TgRBFOX1 or TgU2AF2 mice.

    Article Snippet: Human RBFOX1 cDNA (from pENTR-A2BP1, Addgene, 16176) or human U2AF2 cDNA (from pCDNA3-U2AF65-DYK, GenScript, OHu17874) were independently cloned into a plasmid containing a bidirectional TetO sequence that also harbors the β-galactosidase (β-Gal) reporter with a NLS (pBI-G, Clontech, 631004).

    Techniques: Expressing, Control, Construct, Immunohistochemistry

    (A) Gel shows RT-PCR amplification of Tg-RBFOX1 or TgU2AF2 mRNA in wild-type, MildTgRBFOX1 or MildTgU2AF2 and StrongTgRBFOX1 or StrongTgU2AF2 mice. (B) Histogram shows brain weight of WT (n=5/n=8), MildTgRBFOX1 (n=7) or MildTgU2AF2 (n=5) and Strong TgRBFOX1 (n=7) or Strong TgU2AF2 (n=6) mice (ANOVA, followed by Tukey’s post hoc test; *P < 0.05;**P < 0.01; ***P < 0.001).

    Journal: bioRxiv

    Article Title: Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology

    doi: 10.1101/2024.11.06.622223

    Figure Lengend Snippet: (A) Gel shows RT-PCR amplification of Tg-RBFOX1 or TgU2AF2 mRNA in wild-type, MildTgRBFOX1 or MildTgU2AF2 and StrongTgRBFOX1 or StrongTgU2AF2 mice. (B) Histogram shows brain weight of WT (n=5/n=8), MildTgRBFOX1 (n=7) or MildTgU2AF2 (n=5) and Strong TgRBFOX1 (n=7) or Strong TgU2AF2 (n=6) mice (ANOVA, followed by Tukey’s post hoc test; *P < 0.05;**P < 0.01; ***P < 0.001).

    Article Snippet: Human RBFOX1 cDNA (from pENTR-A2BP1, Addgene, 16176) or human U2AF2 cDNA (from pCDNA3-U2AF65-DYK, GenScript, OHu17874) were independently cloned into a plasmid containing a bidirectional TetO sequence that also harbors the β-galactosidase (β-Gal) reporter with a NLS (pBI-G, Clontech, 631004).

    Techniques: Reverse Transcription Polymerase Chain Reaction, Amplification

    ( A ) Venn diagram showing the 83 genes in the intersection between the 245 genes with exons mis-spliced in Huntington’s disease 15 and the 543 genes with RBFOX-direct target exons 25 ( B ) Venn diagram showing the 76 genes in the intersection between the 245 genes with exons mis-spliced in Huntington’s disease 15 and the 966 genes that are functional targets of Rbfox1 according to Supplementary Table 1. Representation factor (RF) was determined with Two-sided Fisher’s Exact test, using as background genes the human-mouse orthologous genes coincidentally detected in the human and mouse RNA-seq datasets used to define the Huntington’s disease mis-splicing signature 15 ( n = 12,882).

    Journal: bioRxiv

    Article Title: Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology

    doi: 10.1101/2024.11.06.622223

    Figure Lengend Snippet: ( A ) Venn diagram showing the 83 genes in the intersection between the 245 genes with exons mis-spliced in Huntington’s disease 15 and the 543 genes with RBFOX-direct target exons 25 ( B ) Venn diagram showing the 76 genes in the intersection between the 245 genes with exons mis-spliced in Huntington’s disease 15 and the 966 genes that are functional targets of Rbfox1 according to Supplementary Table 1. Representation factor (RF) was determined with Two-sided Fisher’s Exact test, using as background genes the human-mouse orthologous genes coincidentally detected in the human and mouse RNA-seq datasets used to define the Huntington’s disease mis-splicing signature 15 ( n = 12,882).

    Article Snippet: Human RBFOX1 cDNA (from pENTR-A2BP1, Addgene, 16176) or human U2AF2 cDNA (from pCDNA3-U2AF65-DYK, GenScript, OHu17874) were independently cloned into a plasmid containing a bidirectional TetO sequence that also harbors the β-galactosidase (β-Gal) reporter with a NLS (pBI-G, Clontech, 631004).

    Techniques: Functional Assay, RNA Sequencing